Dialysis-dependent renal failure at diagnosis continues to be associated with very poor outcome in multiple myeloma

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Dialysis-dependent renal failure at diagnosis continues to be associated with very poor outcome in multiple myeloma.

We read with great interest the study by Pozzi et al (2013), using data collected from the Modena Cancer Registry from 1989 to 2009, that shows improvement in survival of multiple myeloma (MM) patients over time, especially after 2006. Although several studies have now shown improved overall survival (OS) for MM patients treated in the era of novel agents (bortezomib, lenalidomide, thalidomide)...

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At which stage of renal failure should dialysis be started?

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The Patient Presenting with Renal Failure Due to Multiple Myeloma Associated with Celiac Disease: Case Report

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Multiple myeloma presented as acute renal failure

Multiple myeloma (MM) is a plasma cell dyscrasia and it most often occurs in old age adults. The mean age of the patients at diagnosis is 66 years old and only few percent of patients are younger than 40 years old (1,2). At the time of diagnosis, about 3% of MM patients have no M-protein in their serum or urine, based on immunofixation method (1-3). Approximately 50% of MM patients have at leas...

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Multiple myeloma presenting as acute renal failure.

CASE PRESENTATION A 68-year-old African American woman presented to the emergency department after routine blood work with her primary care physician revealed abnormal renal function studies. Six months prior to admission, she began to have nonspecifi c pain in her back, knees, and feet. Degenerative osteoarthritis was diagnosed, and she was treated with conservative measures including physical...

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ژورنال

عنوان ژورنال: British Journal of Haematology

سال: 2014

ISSN: 0007-1048

DOI: 10.1111/bjh.12818